Diploidy of Drosophila imaginal cells is maintained by a transcriptional repressor encoded by escargot.

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Control of imaginal cell development by the escargot gene of Drosophila.

Mutations in the escargot (esg) locus, which codes for a zinc-finger-containing protein with similarity to the product of the snail gene, cause a variety of defects in adult structures such as loss of abdominal cuticle and malformation of the wings and legs. esg RNA is expressed in wing, haltere, leg and genital imaginal discs and in abdominal histoblast nests in the embryo. Expression in imagi...

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BACKGROUND Although most circadian clock components are conserved between Drosophila and mammals, the roles assigned to the CRYPTOCHROME (CRY) proteins are very different: Drosophila CRY functions as a circadian photoreceptor, whereas mammalian CRY proteins (mCRY1 and 2) are transcriptional repressors essential for molecular clock oscillations. RESULTS Here we demonstrate that Drosophila CRY ...

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ژورنال

عنوان ژورنال: Genes & Development

سال: 1994

ISSN: 0890-9369

DOI: 10.1101/gad.8.19.2270